Germaine Cornelissen

Academic Title

    Professor

Education

    Bachelor's
    University of Brussels, Belgium, Physics, B.S., 1969

    Master's
    University of Brussels, Belgium, Physics, M.S., and Science, M.Ed., 1971

    Ph.D.
    University of Brussels, Belgium, Physics, Ph.D. 1976
    Jean De Prins lab

Bio Statement

• 2006-present: Professor, Department of Integrative Biology and Physiology, University of Minnesota.

• 2013-present: Director, Halberg Chronobiology Center.

• 1999-2013: Co-Director, Halberg Chronobiology Center.

• 1992-2006: Senior Research Associate and Director of Biometry, Chronobiology Laboratories, Department of Laboratory Medicine and Pathology (1992-1993) Department of Pediatrics (1994-present), University of Minnesota.

• 1987-1992: Associate Director, Chronobiology Laboratories, Department of Laboratory Medicine and Pathology, University of Minnesota.

• 1987-1992: Assistant Professor, Chronobiology Laboratories, Department of Laboratory Medicine and Pathology, University of Minnesota.

• 1982-1991: Research Associate, Chronobiology Laboratories, Department of Laboratory Medicine and Pathology, University of Minnesota.

• 1979-1982: Research Fellow, Chronobiology Laboratories, Department of Laboratory Medicine and Pathology, University of Minnesota

• 1976-1979: Visiting Research Fellow, Chronobiology Laboratories, Department of Laboratory Medicine and Pathology, University of Minnesota

• 1975: International Visitor, Chronobiology Laboratories, Department of Laboratory Medicine and Pathology, University of Minnesota

• 1974-1976: Fellowship, IRSIA (Brussels, Belgium)

• 1971-1973: Teaching, Lycée Emile Max (Brussels, Belgium)

Publications

Geuter J, Seizer L, Cornelissen Guillaume G, Engin AB, Fuchs D, Schubert C. Diurnal variation of 8-hydroxy-2’-deoxyguanosine in continuous time series of two breast cancer survivors. doi: https://doi.org/10.1101/2023.11.18.23298714

Seizer L, Schiepek G, Cornelissen G, Löchner J. A primer on sampling rates of ambulatory assessments. Psychological Methods. In press.

Gubin D, Danilenko K, Stefani O, Kolomeichuk S, Markov A, Petrov I, Voronin K, Mezhakova M, Borisenkov M, Shigabaeva A, Yuzhakova N, Lobkina S, Weinert D, Cornelissen G. Blue light and temperature actigraphy measures predicting metabolic health are linked to melatonin receptor polymorphism. Biology 2024; 13: 22.

Siegelova J, Havelkova A, Dusek J, Dunklerova L, Lapcikova K, Pohanka M, Dobsak P, Cornelissen G. Night-to-day blood pressure ratio from seven-day/24-h ambulatory blood pressure monitoring by repeated measurements in patients with coronary heart disease. In: Cornelissen G, Siegelova J, Pohanka M, Dobsak P (Eds). Noninvasive Methods in Cardiology 2023. Masaryk University Press, Brno, Czech Republic 2023; 79-87.

Turner AC, Gubin D, Beaty L, Cornelissen G. Application of Mathematica toolkit to data from residents in the Arctic. In: Cornelissen G, Siegelova J, Pohanka M, Dobsak P (Eds). Noninvasive Methods in Cardiology 2023. Masaryk University Press, Brno, Czech Republic 2023; 27-36.

Cornelissen G, Havelkova A, Siegelova J, Gubin D, Beaty LA, Otsuka K. Chronotherapy of blood pressure: beyond comparing morning vs. evening dosing. In: Cornelissen G, Siegelova J, Pohanka M, Dobsak P (Eds). Noninvasive Methods in Cardiology 2023. Masaryk University Press, Brno, Czech Republic 2023; 9-25.

Singh RB, Fedacko J, Verma N, Elkilany G, Elmarghi O, Nabavizadeh F, Hristova K, Hadi N, Chakravorty S, Shukla AK, Hamdy E, Singh J, Shogenova L, Slezak J, Watanabe S, Medvedev O, Cornelissen G. 2023 ICC/ICN/ISC Guideline for the management of heart failure: A report of the International College of Cardiology/International College of Nutrition and Indian Society of ChronoMedicine, Joint Committee on Guidelines, for Developing and Newly Industrialized Countries. World Heart J 2023; 15 (3): in press.

Sandborgh C, Sackett-Lundeen L, Cornelissen G. Circadian rhythm of cortisol in different menstrual cycle stages of clinically healthy women. World Heart J 2023; 15 (1):39-47.

Singh RB, Cornelissen G, Faima G, Sharma KK. Association of covid-19 with circadian alterations in blood pressure, notably at night. Open Journal of Clinical & Medical Case Reports 2023; 9 (23): 2073.

Cornelissen G, Beaty LA, Gubin D, Siegelova J, Havelkova A, Otsuka K. From chronorisk to chronotherapy, with focus on the cardiovascular system. Herald 2023; 1: 29-38.

Havelkova A, Dvorak P, Siegelova J, Dobsak P, Filipensky P, Cornelissen G. Possibilities of interpreting the night-to-day ratio specified by 24-hour blood pressure monitoring. International Journal of Clinical Practice 2023; 2023: 6530295.

Otsuka K, Cornelissen G, Weydahl A, Gubin D, Beaty LA, Murase M. Rules of heliogeomagnetics diversely coordinating biological rhythms and promoting human health. Appl Sci 2023; 13: 951.

Gubin D, Cornelissen G, Stefani O, Weinert D. Special issue on “Research on Circadian Rhythms in Health and Disease”. Appl Sci 2023; 13: 10728.

Otsuka K, Murakami S, Okajima K, Shibata K, Kubo Y, Gubin DG, Beaty LA, Cornelissen G. Appropriate circadian-circasemidian coupling protects blood pressure from morning surge and promotes human resilience and wellbeing. Clinical Interventions in Aging 2023; 18: 755–769.

Gubin D, Vetoshkin A, Shurkevich N, Gapon L, Borisenkov M, Cornelissen G, Weinert D. Chronotype and lipid metabolism in Arctic Sojourn Workers. Chronobiol Int 2023; 40 (9): 1198-1208.

Gubin D, Neroev V, Malishevskaya T, Kolomeichuk S, Cornelissen G, Yuzhakova N, Vlasova A, Weinert D. Depression scores are associated with retinal ganglion cells loss. Journal of Affective Disorders 2023; 333: 290-296.

Otsuka K, Cornelissen G, Kubo Y, Shibata K, Mizuno K, Aiba T, Furukawa S, Ohshima H, Mukai C. Methods for assessing change in brain plasticity at night and psychological resilience during daytime between repeated long-duration space missions. Sci Rep 2023; 13: 10909.

Cornelissen G, Hirota T. Chronobiology and Chronomedicine. From Molecular and Cellular Mechanisms to Whole Body Interdigitating Networks. Royal Society of Chemistry. 2024; 668 pages. https://books.rsc.org/books/edited-volume/2167/Chronobiology-and-ChronomedicineFrom-Molecular-and

Otsuka K, Yamanaka G, Kubo Y, Kikuchi T, Murakami S, Sasaki J, Fukuda J, Saito Y, Cornelissen G. ToCA-MCI for early detection of MCI and assessment of lifestyle interventions to prevent progression from MCI to dementia in elderly villagers. Therapeutic Research 2022; 43 (5): 411-427.

Gubin D, Neroev V, Malishevskaya T, Kolomeichuk S, Weinert D, Yuzhakova N, Nelaeva A, Fillippova Y, Cornelissen G. Daytime lipid metabolism modulated by CLOCK gene is linked to retinal ganglion cells damage in glaucoma. Applied Sciences 2022; 12. 6374. https://doi.org/10.3390/app12136374

Seizer L, Cornelissen-Guillaume G, Schiepek GK, Chamson E, Bliem HR, Schubert C. About-weekly pattern in the dynamic complexity of a healthy subject’s cellular immune activity: a biopsychosocial analysis. Front. Psychiatry 2022; 13: 799214. doi: 10.3389/fpsyt.2022.799214

Otsuka K, Cornelissen G, Furukawa S, Shibata K, Kubo Y, Mizuno K, Aiba T, Ohshima H, Mukai C. Unconscious mind activates central cardiovascular network and promotes adaptation to microgravity possibly anti-aging during 1-year-long spaceflight. Sci Rep 2022; 12: 11862. https://doi.org/10.1038/s41598-022-14858-8

Singh RB, Fedacko J, Souzzi F, Elkilany G, Hristova K, Fatima G, Pella D, Cornelissen G, Issaza A, Pella D, Nanda NC. Pre-heart failure with 2D- and 3D-speckle tracking echocardiography: a comprehensive review. Echocardiography 2022; 39 (2):302-309.

Siegelova J, Cornelissen G, Dusek J, Pohanka M, Dunklerova L, Rakova D, Havelkova A, Dobsak P. Blood pressure control during exercise training: 24-h/7-day ambulatory blood pressure monitoring. Lecture in World Congress on Chronomedicine, 7th Annual Conference of Indian Society of Chronomedicine. In: Noninvasive Methods in Cardiology. Cornelissen G, Siegelova J, Dobsak P (Eds.) Masaryk University, Brno, Czech Republic 2022; 121-135.

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Abstracts

Duprez DA, Jacobs DR, Daniels MR, Andrews L, Brumbach L, Denenberg J, Watanabe K, Cornelissen Guillaume G, Criqui MH, Szklo M, Allison MA. Subclavian artery, thoracic aorta, and coronary artery calcification, age, race/ethnicity and sex distributions: The Multi-Ethnic Study of Atherosclerosis. Circulation 2023; 148 (Suppl 1): A13729.

Duprez DA, Jacobs DR, Daniels MR, Andrews L, Brumbach L, Denenberg J, Watanabe K, Cornelissen Guillaume G, Criqui MH, Szklo M, Allison MA. Associations of subclavian artery calcification with future cardiovascular events and death: The Multi-Ethnic Study of Atherosclerosis. Circulation 2023; 148 (Suppl 1): A13805.

Allen TS, Andrews LI, Brumback LC, Daniels MR, Dennenberg JO, Thomas IC, Cornelissen Guillaume GG, Duprez DA, Jacobs DR Jr, Criqui MH, Allison MA. Association of thoracic aortic calcification with aortic arch stiffness: the Multi-Ethnic Study of Atherosclerosis (MESA). Hypertension 2022; 79: AP139. https://doi.org/10.1161/hyp.79.suppl_1.P139

Siegelova J, Havelkova A, Dusek J, Dunklerova L, Pohanka M, Dobsak P, Cornelissen G. Blood pressure variability at rest and during aerobic exercises in women with ischemic cardiac diseases. J Hypertension 2022; 40 (e-Supplement 1): e112.

Cornelissen G, for the BIOCOS Investigators and the Phoenix Study Group. Rhythm alterations as sensitive gauges of aging and cardiovascular disease. ICC10 - International Congress of Cardiology & Cardiovascular Imaging 26th -27th March, 2021. Dusit Thani Dubai Hotel- Dubai, UAE.

Cornelissen G. Should blood pressure threshold values be gender specific? 15th Annual University of Minnesota Women’s Health Research Conference: Stigma, Racism and Women’s Health.

Gvozdjakova A, Cornélissen G, Kucharska J, Pella D, Fedacko J, Singh RB. Targeting coenzyme Q10 therapy in prevention of statin-induced mitochondrial myopathy. 21. World Congress of Clinical Nutrition, October 6-8, 2017, Budapest, Hungary, p. 125.

Cornélissen G. Chronobiology of nutrition. 21. World Congress of Clinical Nutrition, October 6-8, 2017, Budapest, Hungary, p. 78.

Gvozdjakova A, Kucharska I, Mojto V, Singh RB, Sharma K, Cornélissen G. Mitochondrialna Kardiologia. Cardiology Lett 2016 (Suppl 1); 125.

Cornélissen G, BIOCOS Investigators. Lessons learned from worldwide around-the-clock monitoring of blood pressure. World Heart J 2016; 8 (4): 392-393.

Wilson DW, Cornélissen G, Lee Gierke C, Singh RB, Halberg F. The analysis and presentation of chronobiological data. World Heart J 2016; 8 (4): 392.

Lee Gierke C, Tarquini R, Perfetto F, Cornélissen G. Changes with age in the circadian rhythm of circulating melatonin. World Heart J 2016; 8 (4): 391-392.

Chibisov S, Dementyev M, Blagonravov M, Singh RB, Cornélissen G, Halabi GM, Abramova M, Meladze Z, Kharlitskaya E, Shastun S, Eremina I. Diagnostics of cardiovascular desynchronsis in patients with cancer pathology. World Heart J 2016; 8 (4): 389.

Cornélissen G, Breus T, Watanabe Y, Syutkina EV, Masalov A, Otsuka K. Influence of space weather on heart rate and heart rate variability. Abstract, 13th European Space Weather Week, Oostende, Belgium, 18 November 2016.

Siegelova J, Dusek J, Havelkova A, Pohanka M, Dunklerova L, Dobsak P, Kohzuki M, Otsuka K, Singh RB, Cornélissen G. Ambulatory blood pressure monitoring analysed from seven day/ 24 hour record. J of Hypertension 2016; 34: e121-e122.

Cornélissen G. A note on the life and work of Professor Franz Halberg. Franz Halberg Memorial Lecture, 8th International Congress on Cardiovascular Diseases, International College of Cardiology, Recife, Brazil, August 13-15, 2015. World Heart Journal 2015; 7 (4): 219-220.

Singh RB, Takahashi T, Chaves H, El-Kilany G, Hristova K, Shehab A, Cornelissen G. Chronic heart failure: a disease of the brain. Abstract, 8th International Congress on Cardiovascular Diseases, International College of Cardiology, Recife, Brazil, August 13-15, 2015. World Heart Journal 2015; 7 (4): 217-218.

Cornélissen G, Syutkina EV, Masalov A, Breus T, Watanabe Y, Otsuka K. Space weather, the atmosphere, and human health on Earth and in Space. Abstract, 12th European Space Weather Week, Oostende, Belgium, 23-27 November 2015. http://www.stce.be/esww12/program/session_details.php?nr=12#

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